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[87] viXra:2004.0695 [pdf] submitted on 2020-04-30 01:41:33
Authors: George Rajna
Comments: 77 Pages.
A first-of-its-kind nanoparticle-based in vivo imaging technique that may one day be used to help diagnose and even treat cancer has been developed by researchers collaborating from Michigan State, Johns Hopkins and Stanford universities. [50] The hope is that further research into cilia will help untangle the complex relationship between them and cancer, and provide both new insights into some of the drivers of cancer as well as new targets for cancer treatment. [49] Researchers have found that changing the mechanical properties of individual cells disrupts their ability to remain stable, profoundly affecting their health and the health of the tissue that comprises them. [48] Biochemists at the University of Bayreuth and the University of Bonn have now discovered a way to regulate this process which is central to gene expression: Certain actinobacteria contain a protein that binds RNA molecules under blue light and can thereby deactivate them. [47] A new piece of a difficult puzzle-the nature of memory-fell into place this week with a hint at how brain cells change structure when they learn something. [46] Researchers at the University of Alberta have found an important protein in the cells of a deadly infectious parasite, opening the door to less harmful treatment for millions of people suffering from diseases like sleeping sickness in Africa and Chagas disease in South America. [45] The remarkable ability of a small Australian sea snail to produce a colourful purple compound to protect its eggs is proving even more remarkable for its potential in a new anti-cancer pharmaceutical. [44] Gene editing technology is a technology that eliminates the underlying causes of and treats diseases by removing specific genesor editing genes to restore their normal function. In particular, CRISPR gene editing technology is now commonly used for immunotherapy by correcting the genes of immune cells to induce them to attack cancer cells selectively. [43]
Category: Physics of Biology
[86] viXra:2004.0692 [pdf] submitted on 2020-04-30 03:34:11
Authors: George Rajna
Comments: 55 Pages.
Light-emitting nanosensors have been used to measure chemical signals that propagate through living plants in response to damage. [36]
Researchers at the Center for Nanoparticle Research, within the Institute for Basic Science (IBS, South Korea) in collaboration with collaborators at Zhejiang University, China, have reported a highly sensitive and specific nanosensor that can monitor dynamic changes of potassium ions in mice undergoing epileptic seizures, indicating their intensity and origin in the brain. [35]
The lab of Cheryl Kerfeld at Michigan State University has created a synthetic nano-sized factory, based on natural ones found in bacteria. [34]
Category: Physics of Biology
[85] viXra:2004.0687 [pdf] submitted on 2020-04-30 07:20:22
Authors: George Rajna
Comments: 75 Pages.
Researchers at Western and Suncor are teaming up to use algae as a way to produce serological test kits for COVID-19 – a new process that overcomes shortfalls of existing processes while saving money. [45]
Researchers in Brazil analyzed the growth of confirmed infected COVID-19 cases across four continents to better characterize the spread of the virus and examine which strategies are effective in reducing its spread. [44]
A system that checks from a safe distance whether someone is displaying symptoms of COVID-19 has been developed by Urs Schneider and colleagues at the Fraunhofer Institute for Manufacturing Engineering and Automation in Stuttgart, Germany. [43]
Category: Physics of Biology
[84] viXra:2004.0686 [pdf] submitted on 2020-04-30 07:52:14
Authors: George Rajna
Comments: 75 Pages.
A Rutgers engineer has created a mathematical model that accurately estimates the death toll linked to the COVID-19 pandemic in the United States and could be used around the world. [45] Researchers in Brazil analyzed the growth of confirmed infected COVID-19 cases across four continents to better characterize the spread of the virus and examine which strategies are effective in reducing its spread. [44] A system that checks from a safe distance whether someone is displaying symptoms of COVID-19 has been developed by Urs Schneider and colleagues at the Fraunhofer Institute for Manufacturing Engineering and Automation in Stuttgart, Germany. [43] Although the test still needs to be tested on intact viral RNA from patient samples, it could help relieve the current pressure on PCR-based tests, the researchers say. [42] Simon Fraser University researchers will use their pioneering imaging technology-called Mango, for its bright colour-to develop coronavirus testing kits. [41] According to the Centers for Disease Control and Prevention, common human coronaviruses usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. [40] When diseases reinforce each other, they rapidly accelerate through the population, then fizzle out as they run out of new hosts. [39] It's no coincidence that some of the worst viral disease outbreaks in recent years-SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus-originated in bats. [38] An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. [37]
Category: Physics of Biology
[83] viXra:2004.0685 [pdf] submitted on 2020-04-30 08:18:47
Authors: George Rajna
Comments: 55 Pages.
The researchers were able to use magnetism to hold 'magnetically responsive' microscopic drug carriers at chosen sites, even in the presence of external forces, such as flowing liquid, which would normally displace them. [32]
A Japanese research team has developed a cyclic peptide (a chain of amino acids bonded circularly) that enhances blood-brain barrier (BBB) penetration. [31]
MIT engineers have designed tiny robots that can help drug-delivery nanoparticles push their way out of the bloodstream and into a tumor or another disease site. [30]
Category: Physics of Biology
[82] viXra:2004.0684 [pdf] submitted on 2020-04-30 08:38:34
Authors: George Rajna
Comments: 39 Pages.
Alzheimer's disease is the sixth leading cause of death in the United States, affecting one in 10 people over the age of 65. Scientists are engineering nanodevices to disrupt processes in the brain that lead to the disease. [25]
A team of researchers at the University of California's Department of Neurological Surgery and the Center for Integrative Neuroscience in San Francisco has taken another step toward the development of a device able to read a person's mind. [24]
Professor Thomas Hills from the Department of Psychology set out to bridge the gap between the philosophical arguments for free will and the neurocognitive realities. [23]
Category: Physics of Biology
[81] viXra:2004.0672 [pdf] submitted on 2020-04-29 03:33:26
Authors: Leonid M. Martyushev
Comments: 4 Pages.
Maximum entropy production principle (MEPP) has been formulated in the mid-twentieth century, and today it has acquired the status of an important principle of science, which is extremely effective in considering various non-equilibrium problems. In this study, for the first time, definition of life is based on an easily measurable physical quantity that is entropy production. Life and evolution are discussed from the point of view of MEPP and the Universe, but not a human.
Category: Physics of Biology
[80] viXra:2004.0670 [pdf] submitted on 2020-04-29 03:55:07
Authors: George Rajna
Comments: 74 Pages.
Researchers in Brazil analyzed the growth of confirmed infected COVID-19 cases across four continents to better characterize the spread of the virus and examine which strategies are effective in reducing its spread. [44]
A system that checks from a safe distance whether someone is displaying symptoms of COVID-19 has been developed by Urs Schneider and colleagues at the Fraunhofer Institute for Manufacturing Engineering and Automation in Stuttgart, Germany. [43]
Although the test still needs to be tested on intact viral RNA from patient samples, it could help relieve the current pressure on PCR-based tests, the researchers say. [42] Simon Fraser University researchers will use their pioneering imaging technology-called Mango, for its bright colour-to develop coronavirus testing kits. [41] According to the Centers for Disease Control and Prevention, common human coronaviruses usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. [40] When diseases reinforce each other, they rapidly accelerate through the population, then fizzle out as they run out of new hosts. [39] It's no coincidence that some of the worst viral disease outbreaks in recent years-SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus-originated in bats. [38] An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. [37] David Baker, Professor of Biochemistry and Director of the Institute for Protein Design at the University of Washington will speak about how algorithmic processes such as de novo design predict protein structures, protein folding mechanisms, and new protein functions. [36] A research team at Kobe University has developed a method of artificially controlling the anchorage position of target proteins in engineered baker's yeast (Saccharomyces cerevisiae). [35]
Category: Physics of Biology
[79] viXra:2004.0669 [pdf] submitted on 2020-04-29 05:31:24
Authors: George Rajna
Comments: 76 Pages.
Shalom Kalnicki, chairman of the radiation oncology department at Montefiore Medical Center in New York, highlighted the challenges faced by radiation oncologists, physicians and medical physicists looking to treat cancer patients in the time of COVID-19. [44]
A system that checks from a safe distance whether someone is displaying symptoms of COVID-19 has been developed by Urs Schneider and colleagues at the Fraunhofer Institute for Manufacturing Engineering and Automation in Stuttgart, Germany. [43]
Although the test still needs to be tested on intact viral RNA from patient samples, it could help relieve the current pressure on PCR-based tests, the researchers say. [42] Simon Fraser University researchers will use their pioneering imaging technology-called Mango, for its bright colour-to develop coronavirus testing kits. [41] According to the Centers for Disease Control and Prevention, common human coronaviruses usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. [40] When diseases reinforce each other, they rapidly accelerate through the population, then fizzle out as they run out of new hosts. [39] It's no coincidence that some of the worst viral disease outbreaks in recent years-SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus-originated in bats. [38] An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. [37] David Baker, Professor of Biochemistry and Director of the Institute for Protein Design at the University of Washington will speak about how algorithmic processes such as de novo design predict protein structures, protein folding mechanisms, and new protein functions. [36] A research team at Kobe University has developed a method of artificially controlling the anchorage position of target proteins in engineered baker's yeast (Saccharomyces cerevisiae). [35]
Category: Physics of Biology
[78] viXra:2004.0652 [pdf] submitted on 2020-04-28 05:26:57
Authors: George Rajna
Comments: 42 Pages.
Tsukuba has used neutron crystallography to reveal high-resolution structural details of a very large oxidase protein. [30] Polymer gels, a gel type with unique properties, have piqued the interest of researchers because of their potential uses in medical applications. [29] Tensorial neutron tomography promises new insights into superconductors, battery electrodes and other energy-related materials. [28] CERN's nuclear physics facility, ISOLDE, has minted a new coin in its impressive collection of isotopes. [27] In the case of several light nuclei, experimental confirmation of the individualism or family nature of nucleons will now be simpler, thanks to predictions presented by Polish physicists from Cracow and Kielce. [26] The identification of the magic number of six provides an avenue to investigate the origin of spin-orbit splittings in atomic nuclei. [25] Now, physicists are working toward getting their first CT scans of the inner workings of the nucleus. [24] The process of the sticking together of quarks, called hadronisation, is still poorly understood. [23] In experimental campaigns using the OMEGA EP laser at the Laboratory for Laser Energetics (LLE) at the University of Rochester, Lawrence Livermore National Laboratory (LLNL), University of California San Diego (UCSD) and Massachusetts Institute of Technology (MIT) researchers took radiographs of the shock front, similar to the X-ray radiology in hospitals with protons instead of X-rays. [22] Researchers generate proton beams using a combination of nanoparticles and laser light. [21] Devices based on light, rather than electrons, could revolutionize the speed and security of our future computers. However, one of the major challenges in today's physics is the design of photonic devices, able to transport and switch light through circuits in a stable way. [20]
Category: Physics of Biology
[77] viXra:2004.0651 [pdf] submitted on 2020-04-28 07:47:42
Authors: George Rajna
Comments: 72 Pages.
Researchers are proposing a possible COVID-19 vaccine that could be good news for resisting current and future pandemics, as well as for the needle-phobic: inhalable vaccines. [42] Simon Fraser University researchers will use their pioneering imaging technology-called Mango, for its bright colour-to develop coronavirus testing kits. [41] According to the Centers for Disease Control and Prevention, common human coronaviruses usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. [40] When diseases reinforce each other, they rapidly accelerate through the population, then fizzle out as they run out of new hosts. [39] It's no coincidence that some of the worst viral disease outbreaks in recent years-SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus-originated in bats. [38] An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. [37] David Baker, Professor of Biochemistry and Director of the Institute for Protein Design at the University of Washington will speak about how algorithmic processes such as de novo design predict protein structures, protein folding mechanisms, and new protein functions. [36] A research team at Kobe University has developed a method of artificially controlling the anchorage position of target proteins in engineered baker's yeast (Saccharomyces cerevisiae). [35] Scientists have found a new way to home in on the proteins covering a particular cell's surface. The feat offers insight into how brain cells form intricate networks during development. [34]
Category: Physics of Biology
[76] viXra:2004.0630 [pdf] submitted on 2020-04-27 08:12:40
Authors: V. A. Kasimov
Comments: 9 Pages. in Russian, in English
The significance of the epidemic 2020 in Russia as of 01.05.2020 is estimated in comparison with China, the USA, Italy and other mass phenomena.
Category: Physics of Biology
[75] viXra:2004.0621 [pdf] submitted on 2020-04-27 08:28:04
Authors: George Rajna
Comments: 41 Pages.
"The new findings now make it possible to study the individual genes of the virus much more precisely than before," says Professor Lars Dölken, head of the JMU Chair of Virology. [25]
It's very modular, and doesn't require custom designs for each compound, which may help treatment development in the future." [24]
However, the rising popularity of nanobiomaterials (NBMs) also raises questions about their potential adverse effects on the environment after excretion and release. [23]
Nuclear technology companies Phoenix and SHINE Medical Technologies have achieved a new world record for a nuclear fusion reaction in a steady-state system, the strongest of its kind ever produced on Earth. [22]
Category: Physics of Biology
[74] viXra:2004.0618 [pdf] submitted on 2020-04-27 09:52:12
Authors: George Rajna
Comments: 39 Pages.
University of Texas at Dallas researchers have developed a promising method for remotely stimulating activity in deep brain regions, advancing understanding of how molecules act in the brain and paving the way for better cancer treatments and therapies for other diseases. [25]
Category: Physics of Biology
[73] viXra:2004.0608 [pdf] submitted on 2020-04-26 01:50:11
Authors: George Rajna
Comments: 42 Pages.
The method alongside optical fiber-based endoscope and photometry will allow real-time potassium imaging in freely moving animals. [25]
A team of researchers at the University of California's Department of Neurological Surgery and the Center for Integrative Neuroscience in San Francisco has taken another step toward the development of a device able to read a person's mind. [24]
Professor Thomas Hills from the Department of Psychology set out to bridge the gap between the philosophical arguments for free will and the neurocognitive realities. [23]
Researchers at the University of Twente have designed a tiny needle in which micro-channels can be used for extracting small liquid samples from a local area of the brain. [22]
Category: Physics of Biology
[72] viXra:2004.0607 [pdf] submitted on 2020-04-26 03:41:38
Authors: George Rajna
Comments: 40 Pages.
It's very modular, and doesn't require custom designs for each compound, which may help treatment development in the future." [24]
However, the rising popularity of nanobiomaterials (NBMs) also raises questions about their potential adverse effects on the environment after excretion and release. [23]
Nuclear technology companies Phoenix and SHINE Medical Technologies have achieved a new world record for a nuclear fusion reaction in a steady-state system, the strongest of its kind ever produced on Earth. [22]
Category: Physics of Biology
[71] viXra:2004.0606 [pdf] submitted on 2020-04-26 04:57:42
Authors: George Rajna
Comments: 78 Pages.
The team plans to continue exploring multi-functional graphene towards the cancer therapy using murine animal model. [50]
Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences and Tsinghua University (THU) report a sandwiched superstructure for graphene oxide (GO) that transports through cell membranes. [49]
The wonder-material graphene could hold the key to unlocking the next generation of advanced, early stage lung cancer diagnosis. [48] Now, researchers from Brown University's School of Engineering have explained how the phenomenon works, and that explanation could pave the way for a new type of controlled molecular self-assembly. [47] The team has turned graphene oxide (GO) into a soft, moldable and kneadable play dough that can be shaped and reshaped into free-standing, three-dimensional structures. [46]
Category: Physics of Biology
[70] viXra:2004.0602 [pdf] submitted on 2020-04-25 13:19:20
Authors: Massimo Fioranelli, Alireza Sepehri, Maria Grazia Roccia, Aroonkumar Beesham
Comments: 26 pages, 5 figures
A DNA is built from charged electrons and atoms and has the inductor-like structure. This structure could be divided into linear, toroid and round inductors. These inductors interact with external electromagnetic waves, move and produce some extra waves within the cells. The shapes of these waves are similar to shapes of hexagonal and pentagonal bases of their DNA source. These electromagnetic waves interact with charged particles on the nuclear membranes and lead to their vibrations. By these vibrations, nuclear membranes act like vibrators within a speaker/microphone and some new ultrasound waves are emerged. Thus, DNAs within cells emit both electromagnetic and ultrasound waves. These waves produce some holes in liquids within the nucleus and cells. To fill these holes, some extra hexagonal and pentagonal bases are produced. These bases could join to each other and form some viruses like Coronavirus. To produce these viruses within a cell, its need that wavelength of external waves be shorter than the size of a cell. Thus 5G millimeter waves could be good candidates for applying in constructing Coronaviruses (COVID-19) within biological cells.
Category: Physics of Biology
[69] viXra:2004.0593 [pdf] submitted on 2020-04-25 04:27:09
Authors: George Rajna
Comments: 58 Pages.
Stereotactic ablative radiotherapy (SABR) is a popular method for treating small, inoperable tumours in various anatomical sites. [38]
Using DNA, small silica particles, and carbon nanotubes, researchers of Karlsruhe Institute of Technology (KIT) have developed novel programmable nanocomposites that can be tailored to various applications and programmed to degrade quickly and gently. [37]
Scientists at the Technical University of Munich (TUM) have functionalized a simple rod-like building block with hydroxamic acids at both ends. [36]
Category: Physics of Biology
[68] viXra:2004.0586 [pdf] submitted on 2020-04-25 09:56:46
Authors: George Rajna
Comments: 73 Pages.
A system that checks from a safe distance whether someone is displaying symptoms of COVID-19 has been developed by Urs Schneider and colleagues at the Fraunhofer Institute for Manufacturing Engineering and Automation in Stuttgart, Germany. [43] Although the test still needs to be tested on intact viral RNA from patient samples, it could help relieve the current pressure on PCR-based tests, the researchers say. [42] Simon Fraser University researchers will use their pioneering imaging technology-called Mango, for its bright colour-to develop coronavirus testing kits. [41] According to the Centers for Disease Control and Prevention, common human coronaviruses usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. [40] When diseases reinforce each other, they rapidly accelerate through the population, then fizzle out as they run out of new hosts. [39] It's no coincidence that some of the worst viral disease outbreaks in recent years-SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus-originated in bats. [38] An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. [37] David Baker, Professor of Biochemistry and Director of the Institute for Protein Design at the University of Washington will speak about how algorithmic processes such as de novo design predict protein structures, protein folding mechanisms, and new protein functions. [36] A research team at Kobe University has developed a method of artificially controlling the anchorage position of target proteins in engineered baker's yeast (Saccharomyces cerevisiae). [35] Scientists have found a new way to home in on the proteins covering a particular cell's surface. The feat offers insight into how brain cells form intricate networks during development. [34]
Category: Physics of Biology
[67] viXra:2004.0584 [pdf] submitted on 2020-04-25 10:28:06
Authors: George Rajna
Comments: 59 Pages.
A team of University of Alberta engineers is refining a new imaging technique that could reduce the number of repeat surgeries patients undergo to remove cancerous tumors. [39]
Stereotactic ablative radiotherapy (SABR) is a popular method for treating small, inoperable tumours in various anatomical sites. [38]
Using DNA, small silica particles, and carbon nanotubes, researchers of Karlsruhe Institute of Technology (KIT) have developed novel programmable nanocomposites that can be tailored to various applications and programmed to degrade quickly and gently. [37]
Category: Physics of Biology
[66] viXra:2004.0582 [pdf] submitted on 2020-04-25 11:08:59
Authors: George Rajna
Comments: 74 Pages.
In the wake of the COVID-19 pandemic, the U.S. Centers for Disease Control and Prevention recommends that people wear masks in public. [44]
A system that checks from a safe distance whether someone is displaying symptoms of COVID-19 has been developed by Urs Schneider and colleagues at the Fraunhofer Institute for Manufacturing Engineering and Automation in Stuttgart, Germany. [43]
Although the test still needs to be tested on intact viral RNA from patient samples, it could help relieve the current pressure on PCR-based tests, the researchers say. [42] Simon Fraser University researchers will use their pioneering imaging technology-called Mango, for its bright colour-to develop coronavirus testing kits. [41] According to the Centers for Disease Control and Prevention, common human coronaviruses usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. [40] When diseases reinforce each other, they rapidly accelerate through the population, then fizzle out as they run out of new hosts. [39] It's no coincidence that some of the worst viral disease outbreaks in recent years-SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus-originated in bats. [38] An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. [37] David Baker, Professor of Biochemistry and Director of the Institute for Protein Design at the University of Washington will speak about how algorithmic processes such as de novo design predict protein structures, protein folding mechanisms, and new protein functions. [36] A research team at Kobe University has developed a method of artificially controlling the anchorage position of target proteins in engineered baker's yeast (Saccharomyces cerevisiae). [35] Scientists have found a new way to home in on the proteins covering a particular cell's surface. The feat offers insight into how brain cells form intricate networks during development. [34]
Category: Physics of Biology
[65] viXra:2004.0572 [pdf] submitted on 2020-04-24 04:08:26
Authors: George Rajna
Comments: 42 Pages.
Researchers in The University of Texas at El Paso's Department of Chemistry and Biochemistry have developed a nanohybrid vehicle that can be used to optimally deliver drugs into the human body. [32]
Researchers at The University of Texas at Austin have developed new guidelines for fabricating nanoscale gel materials, or nanogels, that can deliver numerous therapeutic treatments to treat cancer in a precise manner. In addition to enabling the delivery of drugs in response to tumors, their nanogels can target malignant cells (or biomarkers), degrade into nontoxic components and execute multiple clinical functions. [31]
Category: Physics of Biology
[64] viXra:2004.0548 [pdf] submitted on 2020-04-23 08:57:37
Authors: George Rajna
Comments: 53 Pages.
A new way to deliver therapeutic proteins inside the body uses an acoustically sensitive carrier to encapsulate the proteins and ultrasound to image and guide the package to the exact location required, according to Penn State researchers. [31] MIT engineers have designed tiny robots that can help drug-delivery nanoparticles push their way out of the bloodstream and into a tumor or another disease site. [30] Researchers have shown that existing optical fibre technology could be used to produce microscopic 3-D images of tissue inside the body, paving the way towards 3-D optical biopsies. [29] Researchers at MIT, working with surgeons and oncologists at Massachusetts General Hospital (MGH), have now developed a way to improve the accuracy of this surgery, called debulking. [28] Scientists at the University of Bristol have invented a new technology that could lead to the development of a new generation of smart surgical glues and dressings for chronic wounds. [27] Elaborate molecular networks inside living cells enable them to sense and process many signals from the environment to perform desired cellular functions. [26] RNA sequencing is a technique used to analyze entire genomes by looking at the expression of their genes. [25] Researchers from the University of Chicago have developed a high-throughput RNA sequencing strategy to study the activity of the gut microbiome. [24] Today a large international consortium of researchers published a complex but important study looking at how DNA works in animals. [23] Asymmetry plays a major role in biology at every scale: think of DNA spirals, the fact that the human heart is positioned on the left, our preference to use our left or right hand ... [22] Scientists reveal how a 'molecular machine' in bacterial cells prevents fatal DNA twisting, which could be crucial in the development of new antibiotic treatments. [21]
Category: Physics of Biology
[63] viXra:2004.0547 [pdf] submitted on 2020-04-23 09:40:36
Authors: George Rajna
Comments: 73 Pages.
A team of biomaterials scientists and dentists at the UCLA School of Dentistry has developed a nanoparticle that, based on initial experiments in animals, could improve treatment for bone defects. [42] Northeastern chemical engineer Thomas Webster, who specializes in developing nano-scale medicine and technology to treat diseases, is part of a contingency of scientists that are contributing ideas and technology to the Centers for Disease Control and Prevention to fight the COVID-19 outbreak. [41] According to the Centers for Disease Control and Prevention, common human coronaviruses usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. [40] When diseases reinforce each other, they rapidly accelerate through the population, then fizzle out as they run out of new hosts. [39] It's no coincidence that some of the worst viral disease outbreaks in recent years-SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus-originated in bats. [38] An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. [37] David Baker, Professor of Biochemistry and Director of the Institute for Protein Design at the University of Washington will speak about how algorithmic processes such as de novo design predict protein structures, protein folding mechanisms, and new protein functions. [36] A research team at Kobe University has developed a method of artificially controlling the anchorage position of target proteins in engineered baker's yeast (Saccharomyces cerevisiae). [35] Scientists have found a new way to home in on the proteins covering a particular cell's surface. The feat offers insight into how brain cells form intricate networks during development. [34]
Category: Physics of Biology
[62] viXra:2004.0530 [pdf] submitted on 2020-04-22 02:58:46
Authors: George Rajna
Comments: 38 Pages.
Researchers at the University of Louisville have demonstrated a new way to use ultrasound to create pores in blood cells, which allows the molecule trehalose to enter the cells and prevent their degradation when dried for preservation. [25]
A team of researchers at the University of California's Department of Neurological Surgery and the Center for Integrative Neuroscience in San Francisco has taken another step toward the development of a device able to read a person's mind. [24]
Category: Physics of Biology
[61] viXra:2004.0506 [pdf] submitted on 2020-04-21 04:20:19
Authors: George Rajna
Comments: 33 Pages.
Now, a team of scientists in Turkey has demonstrated the fundamental principles of a universal self-assembly process acting on a range of materials—starting from a few atoms-large quantum dots up to nearly 100 trillion atoms-large human cells. [21]
Researchers at Houston Methodist and Rice University have made a discovery that will impact the design of not only drug delivery systems, but also the development of newer applications in water filtration and energy production. [20]
Category: Physics of Biology
[60] viXra:2004.0498 [pdf] submitted on 2020-04-21 08:34:16
Authors: George Rajna
Comments: 72 Pages.
The insides of living cells can be seen in their natural state in greater detail than ever before using a new technique developed by researchers in Japan. [47] Scientists have been using fluorescence microscopy to study the inner workings of biological cells and organisms for decades. [46] Selecting the most effective molecules for drug delivery is often a trial-and-error process, but Cornell engineers are providing some precision thanks to a technique that reveals the performance of those molecules inside living cells. [45] Now, researchers at MIT and elsewhere have developed a system to deliver medical treatments that can be released at precise times, minimally-invasively, and that ultimately could also deliver those drugs to specifically targeted areas such as a specific group of neurons in the brain. [44] Gene editing technology is a technology that eliminates the underlying causes of and treats diseases by removing specific genesor editing genes to restore their normal function. In particular, CRISPR gene editing technology is now commonly used for immunotherapy by correcting the genes of immune cells to induce them to attack cancer cells selectively. [43]
Category: Physics of Biology
[59] viXra:2004.0492 [pdf] submitted on 2020-04-21 12:43:10
Authors: George Rajna
Comments: 61 Pages.
UNSW medical researchers have achieved unprecedented resolution capabilities in single-molecule microscopy to detect interactions between individual molecules within intact cells. [38]
Scientists at the University of Würzburg have been able to boost current super-resolution microscopy by a novel tweak. [37]
"We put the optical microscope under a microscope to achieve accuracy near the atomic scale," said NIST's Samuel Stavis, who served as the project leader for these efforts. [36]
Researchers have designed an interferometer that works with magnetic quasiparticles called magnons, rather than photons as in conventional interferometers. [35]
Category: Physics of Biology
[58] viXra:2004.0491 [pdf] submitted on 2020-04-20 14:03:39
Authors: Alireza Sepehri, Massimo Fioranelli, Maria Grazia Roccia, Aroonkumar Beesham
Comments: 25 pages, 12 figures
In this research, we propose an antenna model for cells and determine the shape and the wavelength of DNA ultrasound waves which are emited or received by dermatologic antenna. In this model, we show that the structure of a DNA within a nucleus is very similar to an inductor within a speaker/microphone and produce some ultrasound waves. We divide the structure of a DNA into several linear and curved inductors. Linear inductors emit linear magnetic fields and curved inductors produce curved waves. Also, DNA inductors are built from hexagonal and pentagonal bases and consequently emit hexagonal and pentagonal waves. On the other hand, nuclear membranes play the role of magnets within a speaker/microphone. Charged particles out and within nucleus, produce some electric fields along nuclear membranes. These fields produce some currents along membranes. These currents emit some magnetic fields which interact with DNA inductors. The interactions between magnetic fields of membrane and DNA inductors lead to their motions. By motions of charged particles within DNA inductors, some currents are emerged. These currents emit some extra magnetic fields. These magnetic fields interact with nuclear membranes and vibrate them. In these conditions, membranes play the role of plastic within a speaker/microphone. By vibrating nuclear membranes, some linear/curved hexagonal/pentagonal ultrasound waves are emerged. Frequency of these waves are more than frequency of light waves and their wavelengths are smaller than size of air molecules. Thus, these waves pass air molecules and propagate in any empty vacuum. These waves could be taken by viral RNAs in COVID-19 and move them. These RNAs act like the round inductors, vibrate and lead to the vibrations of viral membranes. By vibrations of RNA membranes, some new waves are emerged that are taken by dermatologic antennas. Exchanging waves between Covid-19 and dermatologic antennas causes to absrorptions of viruses by biological human’s body. Wavelenths of Coronaviruses are in the range of wavelengths in 5G technology. Thus, using waves in this technology, we can control COVID-19. On the other hand, millimeter waves in 5G technology could be absorbed by the cell membranes. These waves move molecules within cells and produce some stronger waves. These new waves pass the nuclear membranes, move DNAs and produce some hexagonal/pentagonal holes. To fill these holes, some bases are emerged. These bases join to each other and form some viral RNAs like RNAs of Coronaviruses. Thus, millimeter waves in 5G technology could play the role in constructing Coronaviruses within cells.
Category: Physics of Biology
[57] viXra:2004.0473 [pdf] submitted on 2020-04-20 08:20:54
Authors: George Rajna
Comments: 43 Pages.
"The non-invasive quantification of axon diameters using MRI allows clinicians and researchers to identify problems and developmental pathways that arise in the depths of the brain, driving forward treatment and understanding of development and disease progression." [27] Light could replace invasive techniques to measure brain temperature-eliminating the need to place a thermometer in the brain when treating a range of neurological disorders. [26] Now a team led by researchers at the Georgia Institute of Technology has engineered a way of studying the barrier more closely with the intent of helping drug developers do the same. In a new study, the researchers cultured the human blood-brain barrier on a chip, recreating its physiology more realistically than predecessor chips. [25]
Category: Physics of Biology
[56] viXra:2004.0471 [pdf] submitted on 2020-04-20 09:30:20
Authors: George Rajna
Comments: 40 Pages.
The Netherlands, and University of Surrey, UK—seeding the common ground needed to foster reliable new contrast potential in OCT. [26]
But now a team at the University of Massachusetts Amherst has discovered, while on their way to better understanding protein nanowires, how to use these biological, electricity conducting filaments to make a neuromorphic memristor, or "memory transistor," device. [25]
A team of researchers at the University of California's Department of Neurological Surgery and the Center for Integrative Neuroscience in San Francisco has taken another step toward the development of a device able to read a person's mind. [24]
Category: Physics of Biology
[55] viXra:2004.0464 [pdf] submitted on 2020-04-19 02:35:10
Authors: George Rajna
Comments: 54 Pages.
A Japanese research team has developed a cyclic peptide (a chain of amino acids bonded circularly) that enhances blood-brain barrier (BBB) penetration. [31] MIT engineers have designed tiny robots that can help drug-delivery nanoparticles push their way out of the bloodstream and into a tumor or another disease site. [30] Researchers have shown that existing optical fibre technology could be used to produce microscopic 3-D images of tissue inside the body, paving the way towards 3-D optical biopsies. [29] Researchers at MIT, working with surgeons and oncologists at Massachusetts General Hospital (MGH), have now developed a way to improve the accuracy of this surgery, called debulking. [28] Scientists at the University of Bristol have invented a new technology that could lead to the development of a new generation of smart surgical glues and dressings for chronic wounds. [27] Elaborate molecular networks inside living cells enable them to sense and process many signals from the environment to perform desired cellular functions. [26] RNA sequencing is a technique used to analyze entire genomes by looking at the expression of their genes. [25] Researchers from the University of Chicago have developed a high-throughput RNA sequencing strategy to study the activity of the gut microbiome. [24] Today a large international consortium of researchers published a complex but important study looking at how DNA works in animals. [23] Asymmetry plays a major role in biology at every scale: think of DNA spirals, the fact that the human heart is positioned on the left, our preference to use our left or right hand ... [22] Scientists reveal how a 'molecular machine' in bacterial cells prevents fatal DNA twisting, which could be crucial in the development of new antibiotic treatments. [21]
Category: Physics of Biology
[54] viXra:2004.0461 [pdf] submitted on 2020-04-19 04:37:37
Authors: George Rajna
Comments: 40 Pages.
Biophysicists from the Moscow Institute of Physics and Technology and the University of Groningen in the Netherlands have visualized a nearly complete transport cycle of the mammalian glutamate transporter homologue from archaea. [22] Using a piece of molecular "Velcro" to attach a light-emitting probe to a protein molecule, University of Wollongong (UOW) researchers have unlocked the mystery of how an important protein goes about repairing damaged DNA in bacteria, with implications for understanding how antibiotic resistance develops. [21] In new research, Hao Yan of Arizona State University and his colleagues describe an innovative DNA walker, capable of rapidly traversing a prepared track. [20] Just like any long polymer chain, DNA tends to form knots. Using technology that allows them to stretch DNA molecules and image the behavior of these knots, MIT researchers have discovered, for the first time, the factors that determine whether a knot moves along the strand or "jams" in place. [19] Researchers at Delft University of Technology, in collaboration with colleagues at the Autonomous University of Madrid, have created an artificial DNA blueprint for the replication of DNA in a cell-like structure. [18] An LMU team now reveals the inner workings of a molecular motor made of proteins which packs and unpacks DNA. [17] Chemist Ivan Huc finds the inspiration for his work in the molecular principles that underlie biological systems. [16] What makes particles self-assemble into complex biological structures? [15] Scientists from Moscow State University (MSU) working with an international team of researchers have identified the structure of one of the key regions of telomerase-a so-called "cellular immortality" ribonucleoprotein. [14] Researchers from Tokyo Metropolitan University used a light-sensitive iridium-palladium catalyst to make "sequential" polymers, using visible light to change how building blocks are combined into polymer chains. [13]
Category: Physics of Biology
[53] viXra:2004.0458 [pdf] submitted on 2020-04-19 05:49:13
Authors: George Rajna
Comments: 68 Pages.
MIT engineers have developed a way to closely track how plants respond to stresses such as injury, infection, and light damage, using sensors made of carbon nanotubes. [41]
Researchers of the Microelectronics Research Unit (MIC) at the University of Oulu, in collaboration with Tampere University, have demonstrated that carbon nanotubes can be used to control the direction of neural cell growth. [40]
Now Shulaker and his team in Department of Electrical Engineering and Computer Science, alongside researchers at Analog Devices, Inc.(ADI) also in Massachusetts USA, have taken on a series of challenges that have hampered carbon nanotube (CNT) computers since the first carbon nanotube transistors were reported in the late 1990s. [39]
Category: Physics of Biology
[52] viXra:2004.0439 [pdf] submitted on 2020-04-18 04:34:53
Authors: George Rajna
Comments: 54 Pages.
Researchers at the University of Illinois at Urbana-Champaign have used molecular dynamics simulations to understand how sodium dodecyl sulfate causes protein unfolding. [29] Biochemists can use electron paramagnetic resonance (EPR) on protein single crystals to determine the ultimate electronic structure of paramagnetic protein intermediates and investigate the relative magnetic tensor to a molecular structure. [28] Random bit sequences are key ingredients of various tasks in modern life and especially in secure communication. In a new study researchers have determined that generating true random bit sequences, classical or quantum, is an impossible mission. [27] A quantum circuit that can unambiguously test for information scrambling in an experiment could help verify the calculations of quantum computers and even shed more light on what happens to quantum information when it falls into a black hole. [26] Researchers at the University of Florence and Istituto dei Sistemi Complessi, in Italy, have recently proved that the invasiveness of quantum measurements might not always be detrimental. [25] Now, researchers in the UK and Israel have created miniscule engines within a block of synthetic diamond, and have shown that electronic superposition can boost their power beyond that of classical devices. [24] In the latest wrinkle to be discovered in cubic boron arsenide, the unusual material contradicts the traditional rules that govern heat conduction, according to a new report by Boston College researchers in today's edition of the journal Nature Communications. [23] Beyond the beauty of this phenomenon, which connects heating processes to topology through an elegant quantization law, the results reported in this work designate heating measurements as a powerful and universal probe for exotic states of matter. [22]
Category: Physics of Biology
[51] viXra:2004.0437 [pdf] submitted on 2020-04-18 06:30:09
Authors: George Rajna
Comments: 68 Pages.
Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have synthesized nanoparticles that can be induced by a change in pH to release a deadly dose of ionized iron within cells. [42]
A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has introduced a novel targeted drug delivery system in the fight against cancer. [41]
One day, hospital patients might be able to ingest tiny robots that deliver drugs directly to diseased tissue, thanks to research being carried out at EPFL and ETH Zurich. [40]
Category: Physics of Biology
[50] viXra:2004.0410 [pdf] submitted on 2020-04-17 10:51:26
Authors: George Rajna
Comments: 46 Pages.
Scientists across the globe are rushing to find inhibitors of SARS-CoV-2, the new coronavirus behind the COVID-19 pandemic. [27]
Artificial intelligence (AI) can diagnose COVID-19 from CT scans, researchers in China claim [26]
Researchers in Berlin and Heidelberg have now developed an intelligent neural network that can predict the functions of proteins in the human body. [25]
Category: Physics of Biology
[49] viXra:2004.0394 [pdf] submitted on 2020-04-16 07:51:22
Authors: George Rajna
Comments: 71 Pages.
Although the test still needs to be tested on intact viral RNA from patient samples, it could help relieve the current pressure on PCR-based tests, the researchers say. [42] Simon Fraser University researchers will use their pioneering imaging technology-called Mango, for its bright colour-to develop coronavirus testing kits. [41] According to the Centers for Disease Control and Prevention, common human coronaviruses usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. [40] When diseases reinforce each other, they rapidly accelerate through the population, then fizzle out as they run out of new hosts. [39] It's no coincidence that some of the worst viral disease outbreaks in recent years-SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus-originated in bats. [38] An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. [37] David Baker, Professor of Biochemistry and Director of the Institute for Protein Design at the University of Washington will speak about how algorithmic processes such as de novo design predict protein structures, protein folding mechanisms, and new protein functions. [36] A research team at Kobe University has developed a method of artificially controlling the anchorage position of target proteins in engineered baker's yeast (Saccharomyces cerevisiae). [35] Scientists have found a new way to home in on the proteins covering a particular cell's surface. The feat offers insight into how brain cells form intricate networks during development. [34]
Category: Physics of Biology
[48] viXra:2004.0385 [pdf] submitted on 2020-04-16 09:48:58
Authors: George Rajna
Comments: 39 Pages.
One of the great advantages of X-ray free-electron lasers like the one at the Department of Energy's SLAC National Accelerator Laboratory is that they allow researchers to determine the structure of biological molecules in natural environments. [23] The systematic review of the technology as applied to biology and pharmacology by the MIPT team will no doubt aid other researchers seeking to obtain the structures of key drug targets to develop new medications. [22] A new experimental method permits the X-ray analysis of amyloids, a class of large, filamentous biomolecules which are an important hallmark of diseases such as Alzheimer's and Parkinson's. [12] Thumb through any old science textbook, and you'll likely find RNA described as little more than a means to an end, a kind of molecular scratch paper used to construct the proteins encoded in DNA. [20] Just like any long polymer chain, DNA tends to form knots. Using technology that allows them to stretch DNA molecules and image the behavior of these knots, MIT researchers have discovered, for the first time, the factors that determine whether a knot moves along the strand or "jams" in place. [19] Researchers at Delft University of Technology, in collaboration with colleagues at the Autonomous University of Madrid, have created an artificial DNA blueprint for the replication of DNA in a cell-like structure. [18] An LMU team now reveals the inner workings of a molecular motor made of proteins which packs and unpacks DNA. [17] Chemist Ivan Huc finds the inspiration for his work in the molecular principles that underlie biological systems. [16] What makes particles self-assemble into complex biological structures? [15] Scientists from Moscow State University (MSU) working with an international team of researchers have identified the structure of one of the key regions of telomerase-a so-called "cellular immortality" ribonucleoprotein. [14]
Category: Physics of Biology
[47] viXra:2004.0382 [pdf] submitted on 2020-04-16 10:49:07
Authors: George Rajna
Comments: 38 Pages.
The thin-film perovskite detectors could enable medical and dental imaging at extremely low radiation dose, while also boosting resolution in security scanners and X-ray research applications. [23] Nuclear technology companies Phoenix and SHINE Medical Technologies have achieved a new world record for a nuclear fusion reaction in a steady-state system, the strongest of its kind ever produced on Earth. [22]
Category: Physics of Biology
[46] viXra:2004.0367 [pdf] submitted on 2020-04-15 05:36:19
Authors: George Rajna
Comments: 74 Pages.
Scientists believe about 25 percent of the differences in human life span is determined by genetics-with the rest determined by environmental and lifestyle factors. But they don't yet know all the genes that contribute to a long life. [44] Researchers in Japan have discovered that the DNA inside human cells moves around less when its genes are active. [43] Matthias Wilmanns and colleagues at the European Molecular Biology Laboratory in Hamburg, Germany, developed methods to study the structure of a protein "strain absorber" as it changes during muscle contractions. [42] Using pulsed infrared light lasers, scientists have activated molecules located inside neural tissue with an efficiency of almost 100 percent. [41] DNA damage is occurring in our cells all the time due to external agents, such as exposure to sun, or internal agents, like reactive oxygen species. To detect and repair DNA lesions, cells have evolved DNA damage response. [40] When Greg Bowman presents a slideshow about the proteins he studies, their 3-D shapes and folding patterns play out as animations on a big screen. [39] Researchers at the University of Helsinki uncovered the mechanisms for a novel cellular stress response arising from the toxicity of newly synthesized proteins. [38] Scientists have long sought to develop drug therapies that can more precisely diagnose, target and effectively treat life-threatening illness such as cancer, cardiovascular and autoimmune diseases. [37] Skin cells taken from patients with a rare genetic disorder are up to ten times more sensitive to damage from ultraviolet A (AVA) radiation in laboratory tests, than those from a healthy population, according to new research from the University of Bath. [36] The use of stem cells to repair organs is one of the foremost goals of modern regenerative medicine. [35] Using new technology to reveal the 3-D organization of DNA in maturing male reproductive cells, scientists revealed a crucial period in development that helps explain how fathers pass on genetic information to future generations. [34]
Category: Physics of Biology
[45] viXra:2004.0366 [pdf] submitted on 2020-04-15 06:01:39
Authors: George Rajna
Comments: 41 Pages.
A new study by Adam Diehl, Ningxin Ouyang, and Alan Boyle, University of Michigan Medical School and members of the U-M Center for RNA Biomedicine, shows that transposable elements play an important role in regulating genetic expression with implications to advance the understanding of genetic evolution. [24]
Researchers at Helmholtz Zentrum Muenchen have developed a method to visualize gene expression of cells with an electron microscope. [23]
Researchers at Oregon State University have developed an improved technique for using magnetic nanoclusters to kill hard-to-reach tumors. [22]
Category: Physics of Biology
[44] viXra:2004.0338 [pdf] submitted on 2020-04-14 05:36:19
Authors: George Rajna
Comments: 61 Pages.
The findings, published today in Nature Microbiology, could offer new strategies for fighting infections that don't involve antibiotics. [39]
Engineers at MIT and elsewhere have tracked the evolution of individual cells within an initially benign tumor, showing how the physical properties of those cells drive the tumor to become invasive, or metastatic. [38]
The new treatment employs the alpha particle emitting radionuclide 225Ac. Alpha particles travel a short distance in tissue, thereby limiting their off-target effect. [37]
Category: Physics of Biology
[43] viXra:2004.0336 [pdf] submitted on 2020-04-14 06:04:57
Authors: George Rajna
Comments: 50 Pages.
Quantitative biologists David McCandlish and Juannan Zhou at Cold Spring Harbor Laboratory have developed an algorithm with predictive power, giving scientists the ability to see how specific genetic mutations can combine to make critical proteins change over the course of a species's evolution. [34] Reconstructing evolutionary branches is tricky, especially when many species share a similar type of protein that might have evolved to perform somewhat different functions. [33] Researchers from the The fight against global antibiotic resistance has taken a major step forward with scientists discovering a concept for fabricating nanomeshes as an effective drug delivery system for antibiotics. [30] The solution consisting of colloidal quantum dots is inkjet-printed, creating active photosensitive layer of the photodetector. [29] I'm part of a group of nanotechnology and neuroscience researchers at the University of Washington investigating how quantum dots behave in the brain. [28] Nanotechnology may provide an effective treatment for Parkinson's disease, a team of researchers suggests. [27] Recent research from Kumamoto University in Japan has revealed that polyoxometalates (POMs), typically used for catalysis, electrochemistry, and photochemistry, may also be used in a technique for analyzing quantum dot (QD) photoluminescence (PL) emission mechanisms. [26] Researchers have designed a new type of laser called a quantum dot ring laser that emits red, orange, and green light. [25] The world of nanosensors may be physically small, but the demand is large and growing, with little sign of slowing. [24]
Category: Physics of Biology
[42] viXra:2004.0335 [pdf] submitted on 2020-04-14 08:10:28
Authors: George Rajna
Comments: 69 Pages.
Researchers are developing new peptide-based therapeutics for targeting and disabling the coronavirus' so-called "spike proteins." [40] When diseases reinforce each other, they rapidly accelerate through the population, then fizzle out as they run out of new hosts. [39] It's no coincidence that some of the worst viral disease outbreaks in recent years-SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus-originated in bats. [38] An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. [37] David Baker, Professor of Biochemistry and Director of the Institute for Protein Design at the University of Washington will speak about how algorithmic processes such as de novo design predict protein structures, protein folding mechanisms, and new protein functions. [36] A research team at Kobe University has developed a method of artificially controlling the anchorage position of target proteins in engineered baker's yeast (Saccharomyces cerevisiae). [35] Scientists have found a new way to home in on the proteins covering a particular cell's surface. The feat offers insight into how brain cells form intricate networks during development. [34]
Category: Physics of Biology
[41] viXra:2004.0326 [pdf] submitted on 2020-04-14 10:37:38
Authors: George Rajna
Comments: 70 Pages.
Scientists have been using fluorescence microscopy to study the inner workings of biological cells and organisms for decades. [46] Selecting the most effective molecules for drug delivery is often a trial-and-error process, but Cornell engineers are providing some precision thanks to a technique that reveals the performance of those molecules inside living cells. [45] Now, researchers at MIT and elsewhere have developed a system to deliver medical treatments that can be released at precise times, minimally-invasively, and that ultimately could also deliver those drugs to specifically targeted areas such as a specific group of neurons in the brain. [44] Gene editing technology is a technology that eliminates the underlying causes of and treats diseases by removing specific genesor editing genes to restore their normal function. In particular, CRISPR gene editing technology is now commonly used for immunotherapy by correcting the genes of immune cells to induce them to attack cancer cells selectively. [43]
Category: Physics of Biology
[40] viXra:2004.0307 [pdf] submitted on 2020-04-13 03:44:26
Authors: George Rajna
Comments: 68 Pages.
At the Max Planck Institute for Infection Biology in Berlin, a research team led by Director Thomas F Meyer has developed a model of the human lung epithelium on which to test compounds to combat the SARS-CoV-2 coronavirus. [40] When diseases reinforce each other, they rapidly accelerate through the population, then fizzle out as they run out of new hosts. [39] It's no coincidence that some of the worst viral disease outbreaks in recent years-SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus-originated in bats. [38] An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. [37] David Baker, Professor of Biochemistry and Director of the Institute for Protein Design at the University of Washington will speak about how algorithmic processes such as de novo design predict protein structures, protein folding mechanisms, and new protein functions. [36] A research team at Kobe University has developed a method of artificially controlling the anchorage position of target proteins in engineered baker's yeast (Saccharomyces cerevisiae). [35] Scientists have found a new way to home in on the proteins covering a particular cell's surface. The feat offers insight into how brain cells form intricate networks during development. [34]
Category: Physics of Biology
[39] viXra:2004.0306 [pdf] submitted on 2020-04-13 04:17:31
Authors: George Rajna
Comments: 65 Pages.
Susanne Hellmuth and Olaf Stemmann from the chair of genetics at the University of Bayreuth have now discovered a previously unknown mechanism that regulates the activity of the separase. [34]
A team of UNSW scientists at the School of Biotechnology and Biomolecular Sciences led by Professor Andrew Brown have shown how a key enzyme that contributes to cholesterol production can be regulated—and destroyed—using a particular molecule. [33]
Synthetic proteins have been created that move in response to their environment in predictable and tunable ways. [32]
Category: Physics of Biology
[38] viXra:2004.0304 [pdf] submitted on 2020-04-13 04:45:12
Authors: George Rajna
Comments: 59 Pages.
Researchers investigated the group of microorganisms classified as Asgard archaea, and found a protein in their membrane which acts as a miniature light-activated pump. [32] Proton CT is proposed as an alternative to X-ray CT for acquiring relative stopping power (RSP) maps for use in proton treatment planning. [31] Since protons were first used to treat hospital cancer patients in the early 1990s, around 100 000 people have benefited from this alternative form of radiation therapy. [30] Researchers have moved closer to the real-time verification of hadron therapy, demonstrating the in vivo accuracy of simulations that predict particle range in the patient. [29] A biomimetic nanosystem can deliver therapeutic proteins to selectively target cancerous tumors, according to a team of Penn State researchers. [28] Sunlight is essential for all life, and living organisms have evolved to sense and respond to light. [27] Using X-ray laser technology, a team led by researchers of the Paul Scherrer Institute PSI has recorded one of the fastest processes in biology. [26] A Virginia Commonwealth University researcher has developed a procedure for identifying the source of cells present in a forensic biological sample that could change how cell types are identified in samples across numerous industries. [25] In work at the National Institute of Standards and Technology (NIST) and the University of Maryland in College Park, researchers have devised and demonstrated a new way to measure free energy. [24] A novel technique developed by researchers at the ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP) will help shine new light on biological questions by improving the quality and quantity of information that can be extracted in fluorescence microscopy. [23]
Category: Physics of Biology
[37] viXra:2004.0302 [pdf] submitted on 2020-04-13 07:58:16
Authors: George Rajna
Comments: 61 Pages.
MIT researchers have now devised a way to remotely control the release of the Institute for Protein Design at the University of Washington will speak about how algorithmic processes such as de novo design predict protein structures, protein folding mechanisms, and new protein functions. [36] A research team at Kobe University has developed a method of artificially controlling the anchorage position of target proteins in engineered baker's yeast (Saccharomyces cerevisiae). [35] Scientists have found a new way to home in on the proteins covering a particular cell's surface. The feat offers insight into how brain cells form intricate networks during development. [34]
Category: Physics of Biology
[36] viXra:2004.0295 [pdf] submitted on 2020-04-12 14:36:29
Authors: Bing Luo
Comments: 5 Pages.
In blood circulation (systemic circulation), the order of blood circulation is that arterial blood flows into capillaries only after venous blood refluxes. The human body controls the flow of arterial blood into capillaries by controlling the flow of venous blood. The refluxing power of venous blood changes with the rotation and revolution of the earth, and leads to changes in arterial blood obtained by cells, tissues and organs. If the refluxing power of venous blood of the lungs has a problem, the actual amount of blood obtained by the lungs will be less than the amount of blood distributed to the lungs by the human body (supplying the lungs with nutrients and oxygen they need), and what Pasteur called “the terrain” (There is a paragraph in Seasons of Life: “On his deathbed, Louis Pasteur, the founder of the germ theory of disease, allegedly said, ‘the germ is nothing, the terrain is everything’.”) will form in the lungs.
Category: Physics of Biology
[35] viXra:2004.0286 [pdf] submitted on 2020-04-12 04:41:55
Authors: George Rajna
Comments: 64 Pages.
"But this finding suggests a new direction for developing nanoparticles for drug delivery to the brain by targeting LAT1 molecules." [36]
Johns Hopkins researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a "suicide gene" to pediatric brain tumor cells implanted in the brains of mice. [35]
A new study at the University of Georgia has found a way to attack cancer cells that is potentially less harmful to the patient. [34]
Category: Physics of Biology
[34] viXra:2004.0280 [pdf] submitted on 2020-04-12 05:39:59
Authors: George Rajna
Comments: 75 Pages.
In an effort to make highly sensitive sensors to measure sugar and other vital signs of human health, Iowa State University's Sonal Padalkar figured out how to deposit nanomaterials on cloth and paper. [42] Bioengineers can design smart drugs for antibody and nanomaterial-based therapies to optimize drug efficiency for increasingly efficient, early-stage preclinical trials. [41] Many of these products use nanomaterials, but little is known about how these modern materials and their tiny particles interact with the environment and living things. [40] When chemists from the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw were starting work on a new material designed for the efficient production of nanocrystalline zinc oxide, they didn't expect any surprises. [39] Now writing in Light Science & Applications, Hamidreza Siampour and co-workers have taken a step forward in the field of integrated quantum plasmonics by demonstrating on-chip coupling between a single photon source and plasmonic waveguide. [38] Researchers at University of Utah Health developed a proof-of-concept technology using nanoparticles that could offer a new approach for oral medications. [37] Using scanning tunneling microscopy (STM), extremely high resolution imaging of the molecule-covered surface structures of silver nanoparticles is possible, even down to the recognition of individual parts of the molecules protecting the surface. [36] A fiber optic sensing system developed by researchers in China and Canada can peer inside supercapacitors and batteries to observe their state of charge. [35] The idea of using a sound wave in optical fibers initially came from the team's partner researchers at Bar-Ilan University in Israel. Joint research projects should follow. [34] Researchers at the Technion-Israel Institute of Technology have constructed a first-of-its-kind optic isolator based on resonance of light waves on a rapidly rotating glass sphere. [33]
Category: Physics of Biology
[33] viXra:2004.0277 [pdf] submitted on 2020-04-12 06:12:15
Authors: George Rajna
Comments: 39 Pages.
Physicists at the Center for Integrated Nanostructure Physics (CINAP), within the Institute for Basic Science (IBS, South Korea), have reported a new method to identify the aggregation state of amyloid beta (Aβ) proteins in solution. [25]
For the first time, scientists have developed a computer simulation of how clumps of defective proteins in neurodegenerative diseases like Alzheimer's spread through the brain, much of the time in stealth mode, over as long as 30 years. [24]
Now, researchers at Stevens Institute of Technology and colleagues have modeled how these toxic proteins spread throughout the brain to reproduce the telltale patterns of atrophy associated with Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis, or ALS. [23]
Category: Physics of Biology
[32] viXra:2004.0211 [pdf] submitted on 2020-04-09 02:55:40
Authors: George Rajna
Comments: 49 Pages.
A tiny chemical modification on one of the most abundant and important proteins in cells, actin, has long been somewhat mysterious, its function not fully understood, but scientists from the Perelman School of Medicine at the University of Pennsylvania have now taken a big step towards clearing up the mystery. [27] It's a remarkable choreography. In each of our bodies, more than 37 trillion cells tightly coordinate with other cells to organize into the numerous tissues and organs that make us tick. [26] A Virginia Commonwealth University researcher has developed a procedure for identifying the source of cells present in a forensic biological sample that could change how cell types are identified in samples across numerous industries. [25] In work at the National Institute of Standards and Technology (NIST) and the University of Maryland in College Park, researchers have devised and demonstrated a new way to measure free energy. [24] A novel technique developed by researchers at the ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP) will help shine new light on biological questions by improving the quality and quantity of information that can be extracted in fluorescence microscopy. [23] Micro-computed tomography or "micro-CT" is X-ray imaging in 3-D, by the same method used in hospital CT (or "CAT") scans, but on a small scale with massively increased resolution. [22] A new experimental method permits the X-ray analysis of amyloids, a class of large, filamentous biomolecules which are an important hallmark of diseases such as Alzheimer's and Parkinson's. [12] Thumb through any old science textbook, and you'll likely find RNA described as little more than a means to an end, a kind of molecular scratch paper used to construct the proteins encoded in DNA. [20]
Category: Physics of Biology
[31] viXra:2004.0210 [pdf] submitted on 2020-04-09 03:26:20
Authors: George Rajna
Comments: 49 Pages.
Researchers have discovered the health of the fertilized embryo determines the functional health of the mother, which has implications for healthy aging, stress resilience and suppression of protein damage. [27] It's a remarkable choreography. In each of our bodies, more than 37 trillion cells tightly coordinate with other cells to organize into the numerous tissues and organs that make us tick. [26] A Virginia Commonwealth University researcher has developed a procedure for identifying the source of cells present in a forensic biological sample that could change how cell types are identified in samples across numerous industries. [25] In work at the National Institute of Standards and Technology (NIST) and the University of Maryland in College Park, researchers have devised and demonstrated a new way to measure free energy. [24] A novel technique developed by researchers at the ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP) will help shine new light on biological questions by improving the quality and quantity of information that can be extracted in fluorescence microscopy. [23] Micro-computed tomography or "micro-CT" is X-ray imaging in 3-D, by the same method used in hospital CT (or "CAT") scans, but on a small scale with massively increased resolution. [22] A new experimental method permits the X-ray analysis of amyloids, a class of large, filamentous biomolecules which are an important hallmark of diseases such as Alzheimer's and Parkinson's. [12] Thumb through any old science textbook, and you'll likely find RNA described as little more than a means to an end, a kind of molecular scratch paper used to construct the proteins encoded in DNA. [20] Just like any long polymer chain, DNA tends to form knots. Using technology that allows them to stretch DNA molecules and image the behavior of these knots, MIT researchers have discovered, for the first time, the factors that determine whether a knot moves along the strand or "jams" in place. [19]
Category: Physics of Biology
[30] viXra:2004.0201 [pdf] submitted on 2020-04-09 08:07:03
Authors: George Rajna
Comments: 38 Pages.
The unique design of these nanoparticles reduces the side effects of the drugs, potentially improving patients' quality of life. [28]
Gene editing is one of the hottest topics in cancer research. A Chinese research team has now developed a gold-nanoparticle-based multifunctional vehicle to transport the "gene scissors" to the tumor cell genome. [27]
Category: Physics of Biology
[29] viXra:2004.0191 [pdf] submitted on 2020-04-08 00:58:32
Authors: George Rajna
Comments: 40 Pages.
Visible light communications (VLC), and optical communications overall, caught professor Marcos Katz's interest when he and his team first demonstrated in 2017 a reconfigurable hybrid wireless network exploiting VLC and radio technologies. [24]
A Rutgers-led team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other neurological disorders. [23]
Biology encodes information in DNA and RNA, which are complex molecules finely tuned to their functions. [22]
Category: Physics of Biology
[28] viXra:2004.0189 [pdf] submitted on 2020-04-08 03:16:57
Authors: George Rajna
Comments: 76 Pages.
Tiny biohybrid robots on the micrometer scale can swim through the body and deliver drugs to tumors or provide other cargo-carrying functions. [50]
The hope is that further research into cilia will help untangle the complex relationship between them and cancer, and provide both new insights into some of the drivers of cancer as well as new targets for cancer treatment. [49]
Researchers have found that changing the mechanical properties of individual cells disrupts their ability to remain stable, profoundly affecting their health and the health of the tissue that comprises them. [48]
Category: Physics of Biology
[27] viXra:2004.0178 [pdf] submitted on 2020-04-08 08:51:04
Authors: George Rajna
Comments: 35 Pages.
Now, Azuma Taoka from Kanazawa University, Nobuhiko Nomura from Tsukuba University and colleagues have addressed this question, and demonstrate a previously unrecognized physical heterogeneity in the membrane vesicles of four types of bacterium. [25]
Physicists at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have successfully generated controlled electron pulses in the attosecond range. [24]
A University of Oklahoma physicist, Alberto M. Marino, is developing quantum-enhanced sensors that could find their way into applications ranging from biomedical to chemical detection. [23]
Category: Physics of Biology
[26] viXra:2004.0177 [pdf] submitted on 2020-04-08 09:15:01
Authors: George Rajna
Comments: 66 Pages.
The researchers used nanotechnology in biomedical diagnostics-a process called nanodiagnostics-to create a new, ultrasensitive DNA biosensor. [41] A group of researchers from ITMO University has come up with the concept of a new drug against cancer: a nanorobot made of DNA fragments, which can potentially be used not only to destroy cancer cells, but also to locate them in the body. [40] A team of researchers at the Hebrew University of Jerusalem in Israel has now made such cascades in the lab by encapsulating three enzymes and enzyme cofactors in nanoreactors made from metal-organic framework nanoparticles. [39] Researchers have developed a new form of nanoparticle and associated imaging technique that can detect multiple disease biomarkers, including those for breast cancer, found in deep-tissue in the body. [38] Researchers at University of Utah Health developed a proof-of-concept technology using nanoparticles that could offer a new approach for oral medications. [37] Using scanning tunneling microscopy (STM), extremely high resolution imaging of the molecule-covered surface structures of silver nanoparticles is possible, even down to the recognition of individual parts of the molecules protecting the surface. [36] A fiber optic sensing system developed by researchers in China and Canada can peer inside supercapacitors and batteries to observe their state of charge. [35] The idea of using a sound wave in optical fibers initially came from the team's partner researchers at Bar-Ilan University in Israel. Joint research projects should follow. [34] Researchers at the Technion-Israel Institute of Technology have constructed a first-of-its-kind optic isolator based on resonance of light waves on a rapidly rotating glass sphere. [33] The micro-resonator is a two-mirror trap for the light, with the mirrors facing each other within several hundred nanometers. [32]
Category: Physics of Biology
[25] viXra:2004.0176 [pdf] submitted on 2020-04-08 10:11:37
Authors: George Rajna
Comments: 68 Pages.
Physics experts are working at Europe's CERN lab to create a basic ventilator for mild coronavirus sufferers and recovering patients, the facility said on Wednesday. [40] When diseases reinforce each other, they rapidly accelerate through the population, then fizzle out as they run out of new hosts. [39] It's no coincidence that some of the worst viral disease outbreaks in recent years-SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus-originated in bats. [38] An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. [37] David Baker, Professor of Biochemistry and Director of the Institute for Protein Design at the University of Washington will speak about how algorithmic processes such as de novo design predict protein structures, protein folding mechanisms, and new protein functions. [36] A research team at Kobe University has developed a method of artificially controlling the anchorage position of target proteins in engineered baker's yeast (Saccharomyces cerevisiae). [35] Scientists have found a new way to home in on the proteins covering a particular cell's surface. The feat offers insight into how brain cells form intricate networks during development. [34]
Category: Physics of Biology
[24] viXra:2004.0164 [pdf] replaced on 2020-04-07 19:41:08
Authors: Edward J Steele
Comments: 5 Pages.
The Scientific, Economic and Political issues surrounding the origin and global spread of COVID-19 are discussed.
Category: Physics of Biology
[23] viXra:2004.0156 [pdf] submitted on 2020-04-07 05:00:51
Authors: George Rajna
Comments: 70 Pages.
Scientists have developed a precise, nanotechnology-based treatment to alleviate the pain and fertility problems associated with endometriosis, a common gynecological condition in women of childbearing age. [43] Brazilian and European researchers have demonstrated exactly how a nanotechnology-based compound delivers an oral vaccine against hepatitis B to the immune system. [42]
Category: Physics of Biology
[22] viXra:2004.0155 [pdf] submitted on 2020-04-07 05:22:11
Authors: George Rajna
Comments: 67 Pages.
Researchers in Austria have designed a network of image sensors in which images are encoded as bright pixels with varying optical intensities. [38]
Researchers of the University of Twente and Wageningen University developed a nanosensor that accurately detects biomarkers for cancer in an extremely broad range of concentrations, from 10 particles per microliter to 1 million particles per microliter. [37]
Nanoparticles easily enter into cells. New insights about how they are distributed and what they do there are shown for the first time by high-resolution 3D microscopy images from BESSY II. [36]
Category: Physics of Biology
[21] viXra:2004.0153 [pdf] submitted on 2020-04-07 07:04:19
Authors: V.Korniienko, V.Belocrinicky, I.Vikulin
Comments: 37 Pages. In English and Russian
The cause of the natural hotbeds of the coronavirus pandemic is ambiguous, which causes its rapid development. This reason reveals a technique that shows that matter has a quantum electromagnetic field (QEF) that provides stability to the properties of any matter. It is shown that despite the absence of Sun activity, it generates waves of quantum electromagnetic energies (S-radiations). They contain information whose effect on the QEF of human matter causes the development of coronavirus in his body and the emergence of natural centers of pandemic. Measures have been proposed, the implementation of which will exclude the possibility of the emergence of natural centers of coronavirus and will revive the economy.
Category: Physics of Biology
[20] viXra:2004.0151 [pdf] submitted on 2020-04-07 08:40:31
Authors: George Rajna
Comments: 72 Pages.
Current WHO guidelines for respiratory disease containment are based on a model of droplet spray transmission that dates from the 1930s. [41]
According to the Centers for Disease Control and Prevention, common human coronaviruses usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. [40]
When diseases reinforce each other, they rapidly accelerate through the population, then fizzle out as they run out of new hosts. [39]
Category: Physics of Biology
[19] viXra:2004.0149 [pdf] submitted on 2020-04-07 09:21:40
Authors: George Rajna
Comments: 38 Pages.
In the new work published in Nature Communications, Armin Shayeghi and colleagues demonstrate for the first time quantum interference of the natural polypeptide gramicidin, an antibiotic made of 15 covalently bound amino acids. [22] DNA data storage may become easier to read and write than before, according to researchers at the University of Cambridge Cavendish Laboratory in the U.K. [21] Researchers at the University of Wollongong's (UOW) Molecular Horizons initiative have shed new light on how an important but not well understood protein goes about its vital role of reducing errors and mutations in DNA replication. [20] DNA is a lengthy molecule-approximately 1,000-fold longer than the cell in which it resides-so it can't be jammed in haphazardly. [19] Researchers at Delft University of Technology, in collaboration with colleagues at the Autonomous University of Madrid, have created an artificial DNA blueprint for the replication of DNA in a cell-like structure. [18] An LMU team now reveals the inner workings of a molecular motor made of proteins which packs and unpacks DNA. [17] Chemist Ivan Huc finds the inspiration for his work in the molecular principles that underlie biological systems. [16] What makes particles self-assemble into complex biological structures? [15] Scientists from Moscow State University (MSU) working with an international team of researchers have identified the structure of one of the key regions of telomerase-a so-called "cellular immortality" ribonucleoprotein. [14] Researchers from Tokyo Metropolitan University used a light-sensitive iridium-palladium catalyst to make "sequential" polymers, using visible light to change how building blocks are combined into polymer chains. [13] Researchers have fused living and non-living cells for the first time in a way that allows them to work together, paving the way for new applications. [12] UZH researchers have discovered a previously unknown way in which proteins interact with one another and cells organize themselves. [11]
Category: Physics of Biology
[18] viXra:2004.0136 [pdf] submitted on 2020-04-06 03:47:59
Authors: George Rajna
Comments: 54 Pages.
Intensity-modulated proton therapy (IMPT) delivered via proton pencil-beam scanning (PBS) is one of the most precise methods available to target tumours with high radiation doses while minimizing the impact to surrounding healthy tissue. [30]
Researchers have moved closer to the real-time verification of hadron therapy, demonstrating the in vivo accuracy of simulations that predict particle range in the patient. [29]
A biomimetic nanosystem can deliver therapeutic proteins to selectively target cancerous tumors, according to a team of Penn State researchers. [28]
Category: Physics of Biology
[17] viXra:2004.0133 [pdf] submitted on 2020-04-06 04:54:23
Authors: George Rajna
Comments: 19 Pages.
In a new study published in Nature Communications, a research team from Virginia Tech reported that they had found a substantial collection of genes for metabolic cycles-a defining characteristic of cellular life-in a wide range of "giant viruses." [10] A research team led by physicist Roya Zandi at the University of California, Riverside, has made progress is solving this mystery. [9] A protein involved in cognition and storing long-term memories looks and acts like a protein from viruses. [8] Discovery of quantum vibrations in 'microtubules' inside brain neurons supports controversial theory of consciousness The human body is a constant flux of thousands of chemical/biological interactions and processes connecting molecules, cells, organs, and fluids, throughout the brain, body, and nervous system. Up until recently it was thought that all these interactions operated in a linear sequence, passing on information much like a runner passing the baton to the next runner. However, the latest findings in quantum biology and biophysics have discovered that there is in fact a tremendous degree of coherence within all living systems. The accelerating electrons explain not only the Maxwell Equations and the Special Relativity, but the Heisenberg Uncertainty Relation, the Wave-Particle Duality and the electron's spin also, building the Bridge between the Classical and Quantum Theories. The Planck Distribution Law of the electromagnetic oscillators explains the electron/proton mass rate and the Weak and Strong Interactions by the diffraction patterns. The Weak Interaction changes the diffraction patterns by moving the electric charge from one side to the other side of the diffraction pattern, which violates the CP and Time reversal symmetry. The diffraction patterns and the locality of the self-maintaining electromagnetic potential explains also the Quantum Entanglement, giving it as a natural part of the Relativistic Quantum Theory and making possible to understand the Quantum Biology.
Category: Physics of Biology
[16] viXra:2004.0125 [pdf] submitted on 2020-04-06 08:25:43
Authors: George Rajna
Comments: 43 Pages.
Researchers from TU/e and Radboud University have developed communities of artificial cells that communicate with each other with unprecedented power. [33]
Protocells—artificial cells—that are active and mimic living cells by moving independently and that are biocompatible and enzymatically active are now possible using an improved method developed by Penn State researchers. [32]
Pioneering new research into the way in which cells communicate with each other could hold the key to unlocking new, improved treatment for life-threatening diseases, including cancer. [31]
Category: Physics of Biology
[15] viXra:2004.0124 [pdf] submitted on 2020-04-06 09:21:24
Authors: George Rajna
Comments: 47 Pages.
A collaboration between the National Renewable Energy Laboratory (NREL) and three other national laboratories has yielded new insight into the ability of bacteria to break down the hardy part of a plant known as lignin. [29] By enticing away the repressors dampening unexpressed, silent genes in Streptomyces bacteria, researchers at the University of Illinois have unlocked several large gene clusters for new natural products, according to a study published in the journal Nature Chemical Biology. [28] Imagine trying to figure out how something works when that something takes place in a space smaller than a femtoliter: one quadrillionith of a liter. [27] A new NYU Abu Dhabi study suggests for the first time that actin, which is a cytoskeleton protein found in the cell, is critical to regulating the genome-the genetic material of an organism-during the formation of "neurons" or nerve cells. [26] For the English scientists involved, perhaps the most important fact is that their DNA read was about twice as long as the previous record, held by their Australian rivals. [25] Researchers from the University of Chicago have developed a high-throughput RNA sequencing strategy to study the activity of the gut microbiome. [24] Today a large international consortium of researchers published a complex but important study looking at how DNA works in animals. [23] Asymmetry plays a major role in biology at every scale: think of DNA spirals, the fact that the human heart is positioned on the left, our preference to use our left or right hand ... [22] Scientists reveal how a 'molecular machine' in bacterial cells prevents fatal DNA twisting, which could be crucial in the development of new antibiotic treatments. [21] In new research, Hao Yan of Arizona State University and his colleagues describe an innovative DNA HYPERLINK "https://phys.org/tags/walker/" walker, capable of rapidly traversing a prepared track. [20]
Category: Physics of Biology
[14] viXra:2004.0110 [pdf] submitted on 2020-04-05 03:30:38
Authors: George Rajna
Comments: 56 Pages.
Researchers at Uppsala University have therefore developed an all-organic proton battery that can be charged in a matter of seconds. [31] Since protons were first used to treat hospital cancer patients in the early 1990s, around 100 000 people have benefited from this alternative form of radiation therapy. [30] Researchers have moved closer to the real-time verification of hadron therapy, demonstrating the in vivo accuracy of simulations that predict particle range in the patient. [29] A biomimetic nanosystem can deliver therapeutic proteins to selectively target cancerous tumors, according to a team of Penn State researchers. [28] Sunlight is essential for all life, and living organisms have evolved to sense and respond to light. [27] Using X-ray laser technology, a team led by researchers of the Paul Scherrer Institute PSI has recorded one of the fastest processes in biology. [26] A Virginia Commonwealth University researcher has developed a procedure for identifying the source of cells present in a forensic biological sample that could change how cell types are identified in samples across numerous industries. [25] In work at the National Institute of Standards and Technology (NIST) and the University of Maryland in College Park, researchers have devised and demonstrated a new way to measure free energy. [24] A novel technique developed by researchers at the ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP) will help shine new light on biological questions by improving the quality and quantity of information that can be extracted in fluorescence microscopy. [23] Micro-computed tomography or "micro-CT" is X-ray imaging in 3-D, by the same method used in hospital CT (or "CAT") scans, but on a small scale with massively increased resolution. [22]
Category: Physics of Biology
[13] viXra:2004.0104 [pdf] submitted on 2020-04-05 09:14:59
Authors: George Rajna
Comments: 28 Pages.
A previous study has shown that a type of squill growing in Madeira produces a chemical compound that may be useful as a medicinal drug. [16]
A completely new resistance gene, which is likely to counteract the newest aminoglycoside-drug plazomycin, was recently discovered by scientists in Gothenburg, Sweden. [15]
Now investigators at Massachusetts General Hospital (MGH) have modified the system to be nearly free of this requirement, making it possible to potentially target any location across the entire human genome. [14]
Category: Physics of Biology
[12] viXra:2004.0081 [pdf] submitted on 2020-04-04 02:30:20
Authors: V. A. Kasimov.
Comments: 8 Pages. In Russian, English
At the elementary level, the causes of the virus pandemic 2020 are analyzed. For this purpose, a Bayesian model of decision making is proposed.
Category: Physics of Biology
[11] viXra:2004.0074 [pdf] submitted on 2020-04-04 03:57:07
Authors: George Rajna
Comments: 38 Pages.
A team of researchers from Germany, the Netherlands and Italy has developed a way to use scattered light to map nerve fiber pathway crossing points in the brain. [25]
A team of researchers at the University of California's Department of Neurological Surgery and the Center for Integrative Neuroscience in San Francisco has taken another step toward the development of a device able to read a person's mind. [24]
Professor Thomas Hills from the Department of Psychology set out to bridge the gap between the philosophical arguments for free will and the neurocognitive realities. [23]
Category: Physics of Biology
[10] viXra:2004.0070 [pdf] submitted on 2020-04-04 08:34:40
Authors: Perry W Swanborough
Comments: 6 Pages.
It has been established that heterochiral self-replication of loop structures in cellular automata (CA) spaces cannot be achieved by pooling a state-transition function with its corresponding mirror transition function because some chiral rules specific to right-handed replication are contradicted by chiral rules specific for left-handed replication. A less-strict functional heterochirality of self-reproduction by structures in CA space, notionally achievable by permutation-transformation of structures and transition functions, was hypothesized. Over all possible state-set permutations, it was found that there is no permutation-transformation of the left-handed form of the J. Byl (1989) state-transition function which corresponds to no contradictions with the right-handed (original) transition function. This result demonstrates that the structure’s replication is robustly homochiral.
Category: Physics of Biology
[9] viXra:2004.0058 [pdf] submitted on 2020-04-03 01:43:10
Authors: George Rajna
Comments: 36 Pages.
Reporting April 2 in the journal Science, a team led by the University of Washington School of Medicine has created artificial proteins that function as molecular logic gates. [24]
Collaboration between material scientists, biologists and chemists could advance the development of self-assembling nanomaterials, called nanoarchitectonics, argues a review in the journal Science and Technology of Advanced Materials. [23]
Brown University researchers have made a discovery about the way things stick together at tiny scales that could be helpful in engineering micro- and nanoscale devices. [22]
Category: Physics of Biology
[8] viXra:2004.0053 [pdf] submitted on 2020-04-03 04:53:17
Authors: George Rajna
Comments: 54 Pages.
A team of scientists led by researchers at UC Santa Barbara has discovered that multiple opsin proteins, known for decades to be required for vision, also function as taste receptors. [36] There are an estimated 20,000 to 30,000 proteins at work in cells, where they carry out numerable functions, says computational molecular biologist Roman Sloutsky at the University of Massachusetts Amherst. [35] Are we alone in the universe? It comes down to whether intelligence is a probable outcome of natural selection, or an improbable fluke. [34] Reconstructing evolutionary branches is tricky, especially when many species share a similar type of protein that might have evolved to perform somewhat different functions. [33] Researchers from the The fight against global antibiotic resistance has taken a major step forward with scientists discovering a concept for fabricating nanomeshes as an effective drug delivery system for antibiotics. [30] The solution consisting of colloidal quantum dots is inkjet-printed, creating active photosensitive layer of the photodetector. [29] I'm part of a group of nanotechnology and neuroscience researchers at the University of Washington investigating how quantum dots behave in the brain. [28] Nanotechnology may provide an effective treatment for Parkinson's disease, a team of researchers suggests. [27] Recent research from Kumamoto University in Japan has revealed that polyoxometalates (POMs), typically used for catalysis, electrochemistry, and photochemistry, may also be used in a technique for analyzing quantum dot (QD) photoluminescence (PL) emission mechanisms. [26]
Category: Physics of Biology
[7] viXra:2004.0050 [pdf] submitted on 2020-04-03 07:57:01
Authors: George Rajna
Comments: 70 Pages.
Combining genomic and epidemiological information in this way could allow authorities to better anticipate where a rapid increase in COVID-19 cases is brewing, Weimer said. [41]
According to the Centers for Disease Control and Prevention, common human coronaviruses usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. [40]
When diseases reinforce each other, they rapidly accelerate through the population, then fizzle out as they run out of new hosts. [39]
Category: Physics of Biology
[6] viXra:2004.0048 [pdf] submitted on 2020-04-03 08:15:21
Authors: George Rajna
Comments: 67 Pages.
Researchers at Northwestern and Cornell Universities have developed a new platform that could produce new therapies more than 10 times faster than current methods. [39] It's no coincidence that some of the worst viral disease outbreaks in recent years-SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus-originated in bats. [38] An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. [37] David Baker, Professor of Biochemistry and Director of the Institute for Protein Design at the University of Washington will speak about how algorithmic processes such as de novo design predict protein structures, protein folding mechanisms, and new protein functions. [36] A research team at Kobe University has developed a method of artificially controlling the anchorage position of target proteins in engineered baker's yeast (Saccharomyces cerevisiae). [35] Scientists have found a new way to home in on the proteins covering a particular cell's surface. The feat offers insight into how brain cells form intricate networks during development. [34]
Category: Physics of Biology
[5] viXra:2004.0047 [pdf] submitted on 2020-04-03 08:34:27
Authors: George Rajna
Comments: 70 Pages.
Dibakar Bhattacharyya has been a fixture in the University of Kentucky's College of Engineering for more than 50 years and is renowned for his research, which focuses on incorporating life sciences materials with synthetic membranes for filtering and producing clean water. [41] According to the Centers for Disease Control and Prevention, common human coronaviruses usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. [40] When diseases reinforce each other, they rapidly accelerate through the population, then fizzle out as they run out of new hosts. [39] It's no coincidence that some of the worst viral disease outbreaks in recent years-SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus-originated in bats. [38] An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. [37] David Baker, Professor of Biochemistry and Director of the Institute for Protein Design at the University of Washington will speak about how algorithmic processes such as de novo design predict protein structures, protein folding mechanisms, and new protein functions. [36] A research team at Kobe University has developed a method of artificially controlling the anchorage position of target proteins in engineered baker's yeast (Saccharomyces cerevisiae). [35] Scientists have found a new way to home in on the proteins covering a particular cell's surface. The feat offers insight into how brain cells form intricate networks during development. [34]
Category: Physics of Biology
[4] viXra:2004.0032 [pdf] submitted on 2020-04-02 06:05:36
Authors: George Rajna
Comments: 41 Pages.
Researchers led by biomedical engineers at Tufts University invented a microfluidic chip containing cardiac cells that is capable of mimicking hypoxic conditions following a heart attack—specifically when an artery is blocked in the heart and then unblocked after treatment. [24]
"Sensors with an integrated power supply in such small sizes are also exciting for applications in the area of the Internet of Things, which connects decentralised, autonomous electronic systems," added Adelung. [23]
Category: Physics of Biology
[3] viXra:2004.0027 [pdf] submitted on 2020-04-02 10:24:49
Authors: George Rajna
Comments: 46 Pages.
The researchers say that their discovery could lead to the development of biological computers that use ripples to process information. [28] The discovery that protein therapeutics can hijack the HOPS complex to gain access to the cell interior should help scientists design therapeutic proteins to treat diseases that are not adequately treated using other approaches, Schepartz said. [27] DNA regions susceptible to breakage and loss are genetic hot spots for important evolutionary changes, according to a Stanford study. [26] For the English scientists involved, perhaps the most important fact is that their DNA read was about twice as long as the previous record, held by their Australian rivals. [25] Researchers from the University of Chicago have developed a high-throughput RNA sequencing strategy to study the activity of the gut microbiome. [24] Today a large international consortium of researchers published a complex but important HYPERLINK "https://www.nature.com/articles/s41586-018-0734-6" study looking at how DNA works in animals. [23] Asymmetry plays a major role in biology at every scale: think of DNA spirals, the fact that the human heart is positioned on the left, our preference to use our left or right hand ... [22] Scientists reveal how a 'molecular machine' in bacterial cells prevents fatal DNA twisting, which could be crucial in the development of new antibiotic treatments. [21] In new research, Hao Yan of Arizona State University and his colleagues describe an innovative DNA HYPERLINK "https://phys.org/tags/walker/" walker, capable of rapidly traversing a prepared track. [20] Just like any long polymer chain, DNA tends to form knots. Using technology that allows them to stretch DNA molecules and image the behavior of these knots, MIT researchers have discovered, for the first time, the factors that determine whether a knot moves along the strand or "jams" in place. [19]
Category: Physics of Biology
[2] viXra:2004.0008 [pdf] submitted on 2020-04-01 05:04:41
Authors: George Rajna
Comments: 41 Pages.
The team envision an array of their quantum sensors that can be placed over the heart, giving readings in a matter of seconds. [30] Molecules that are involved in photosynthesis exhibit the same quantum effects as non-living matter, concludes an international team of scientists including University of Groningen theoretical physicist Thomas la Cour Jansen. [29] Nanoparticles derived from tea leaves inhibit the growth of lung cancer cells, destroying up to 80% of them, new research by a joint Swansea University and Indian team has shown. [28] A team of researchers including U of A engineering and physics faculty has developed a new method of detecting single photons, or light particles, using quantum dots. [27] Recent research from Kumamoto University in Japan has revealed that polyoxometalates (POMs), typically used for catalysis, electrochemistry, and photochemistry, may also be used in a technique for analyzing quantum dot (QD) photoluminescence (PL) emission mechanisms. [26] Researchers have designed a new type of laser called a quantum dot ring laser that emits red, orange, and green light. [25] The world of nanosensors may be physically small, but the demand is large and growing, with little sign of slowing. [24] In a joint research project, scientists from the Max Born Institute for Nonlinear Optics and Short Pulse Spectroscopy (MBI), the Technische Universität Berlin (TU) and the University of Rostock have managed for the first time to image free nanoparticles in a laboratory experiment using a highintensity laser source. [23] For the first time, researchers have built a nanolaser that uses only a single molecular layer, placed on a thin silicon beam, which operates at room temperature. [22] A team of engineers at Caltech has discovered how to use computer-chip manufacturing technologies to create the kind of reflective materials that make safety vests, running shoes, and road signs appear shiny in the dark. [21] In the September 23th issue of the Physical Review Letters, Prof. Julien Laurat and his team at Pierre and Marie Curie University in Paris (Laboratoire Kastler Brossel-LKB) report that they have realized an efficient mirror consisting of only 2000 atoms. [20]
Category: Physics of Biology
[1] viXra:2004.0005 [pdf] submitted on 2020-04-01 08:30:09
Authors: George Rajna
Comments: 17 Pages.
On the basis of an empty and therefore non-infectious shell of a phage virus, researchers from Berlin have developed a chemically modified phage capsid that stifles influenza viruses. [9] A protein involved in cognition and storing long-term memories looks and acts like a protein from viruses. [8] Discovery of quantum vibrations in 'microtubules' inside brain neurons supports controversial theory of consciousness The human body is a constant flux of thousands of chemical/biological interactions and processes connecting molecules, cells, organs, and fluids, throughout the brain, body, and nervous system. Up until recently it was thought that all these interactions operated in a linear sequence, passing on information much like a runner passing the baton to the next runner. However, the latest findings in quantum biology and biophysics have discovered that there is in fact a tremendous degree of coherence within all living systems. The accelerating electrons explain not only the Maxwell Equations and the Special Relativity, but the Heisenberg Uncertainty Relation, the Wave-Particle Duality and the electron's spin also, building the Bridge between the Classical and Quantum Theories. The Planck Distribution Law of the electromagnetic oscillators explains the electron/proton mass rate and the Weak and Strong Interactions by the diffraction patterns. The Weak Interaction changes the diffraction patterns by moving the electric charge from one side to the other side of the diffraction pattern, which violates the CP and Time reversal symmetry. The diffraction patterns and the locality of the self-maintaining electromagnetic potential explains also the Quantum Entanglement, giving it as a natural part of the Relativistic Quantum Theory and making possible to understand the Quantum Biology.
Category: Physics of Biology
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